Royals vs White Sox Prediction, Pick, MLB Odds for Wednesday, May 13

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Royals vs White Sox Prediction, Pick, MLB Odds for Wednesday, May 13

The Chicago White Sox host the Kansas City Royals on May 13, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on ROYL. The Royals are favored by -112 on the moneyline and by -1.5 on the run line. The White Sox are -104 on the moneyline and +1.5 on the run line. The total is set at 8 runs. Find my MLB picks and Royals vs White Sox prediction below, as well as probable pitchers, weather report, and more.

Royals vs White Sox Picks:
Bobby Witt Over 1.5 Total Bases (-125, FanDuel)
Bobby Witt Over 0.5 Stolen Bases (+320, FanDuel)

Odds and Spread
Royals vs White Sox Odds
Wednesday, May 13, 7:40 p.m. ET at ROYL
Royals: -1.5 on the run line (+146), Moneyline -112, Over 8 (-110), Under 8 (+110)
White Sox: +1.5 on the run line (-176), Moneyline -104, Over 8 (-110), Under 8 (+110)

Probable Pitchers
Royals vs White Sox Probable Pitchers
Seth Lugo (RHP, KCR) vs Noah Schultz (LHP, CHW)

Betting Preview
The Royals and White Sox will play the second game of a three-game set at Guaranteed Rate Field in Chicago. Kansas City right-hander Seth Lugo is lined up opposite Chicago left-hander Noah Schultz. Schultz has shown an up-and-down start to his rookie season, carrying a 4.68 ERA and 1.32 WHIP, while Lugo brings a steady presence but has had mixed results this year. The Royals’ lineup has cooled a bit recently, dropping three of their last five, while the White Sox have their own offensive questions. Bobby Witt Jr. has begun to find rhythm at the plate, and he could pose a significant threat if Schultz’s command wavers early. Witt’s speed on the bases adds another layer of risk for Chicago, particularly if Schultz relies heavily on off-speed pitches after not locating his four-seam fastball consistently.

Picks discussed above lean on Witt’s power and speed against Schultz, with potential for extra-base hits and stolen bases contributing to a productive night at the plate for Witt.

Weather
Royals vs White Sox Weather: Get the latest coverage on MLB Weather. 

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