Brewers vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 6
On Wednesday in the majors, the Milwaukee Brewers take on the St. Louis Cardinals. Before you check the MLB betting lines on FanDuel Sportsbook, here is the essential information about this matchup.
Game Info
Milwaukee Brewers (18-16) vs. St. Louis Cardinals (21-14)
Date: Wednesday, May 6, 2026
Time: 1:15 p.m. ET
Venue: Busch Stadium — St. Louis, Missouri
Coverage: Cardinals.TV and Brewers.TV
Moneyline: MIL (-110) | STL (-106)
Spread: MIL -1.5 (+152) | STL +1.5 (-184)
Total: 8.5 — Over (+100) | Under (-122)
Pitchers:
Brandon Sproat (Brewers) — 0-2, 6.75 ERA
Andre Pallante (Cardinals) — 3-2, 3.73 ERA
The Brewers will send Brandon Sproat to the mound (0-2, 6.75 ERA) in search of his first win of the season, while the Cardinals will counter with Andre Pallante (3-2, 3.73 ERA). Sproat and his team are 3-1-0 ATS this season when he starts. Sproat’s squad is 2-1 this season when he starts and they are the favorites on the moneyline. The Cardinals are 4-2-0 ATS in Pallante’s six starts that had a set spread. Pallante’s five starts this season in which the Cardinals were under the moneyline have gone 3-2.
All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (56.9%)
The Brewers have gone 13-9, or 59.1%, when they have been listed as a favorite in 22 chances this season. Milwaukee has won 13 times in 22 opportunities when favored by at least -110 on the moneyline. The Brewers and their opponents have combined to go over the total 17 times in 34 games. In 34 games with a presented line, the Brewers are 20-14-0 against the spread.
The Cardinals are 19-13 as moneyline underdogs this season (59.4% wins). When they have been moneyline underdogs with odds of -106 or longer, St. Louis has gone 19-13 (59.4%). In 35 games with an over/under, the Cardinals and opponents have gone over 18 times (18-15-2). The Cardinals have a 22-13-0 mark against the spread this season (covering 62.9%).
Runline and Over/Under
St. Louis is a -106 underdog on the moneyline, while Milwaukee is a -110 favorite on the road. The Cardinals host the Brewers and are +1.5 on the runline. The Cardinals are +152 to cover the spread, and the Brewers are -184. The over/under for the May 6 contest is 8.5, with +100 on the over and -122 on the under.
Key Player
Brice Turang leads Milwaukee in OBP (.434) and total hits (35) this season. He is batting .304 with a .522 slugging percentage. Among all qualifying hitters, Turang ranks 26th in batting average and second in on-base percentage.
Brice Turang is central to Milwaukee’s production this season, and his on-base prowess has helped keep Milwaukee competitive in a number of tight games.
