Royals vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 7
The Thursday MLB slate features a matchup between the Kansas City Royals and the Cleveland Guardians. All the information you need to make smart wagers on this game at FanDuel Sportsbook is below. Check out all of the latest MLB betting lines here.
Game Info:
Date: Thursday, May 7, 2026
Time: 2:10 p.m. ET
Venue: Kauffman Stadium — Kansas City, Missouri
Coverage: Royals.TV and CleGuardians.TV
Betting Info:
Moneyline: KC: (-144) | CLE: (+122)
Spread: KC: -1.5 (+138) | CLE: +1.5 (-166)
Total: 9 — Over: (-122) | Under: (+100)
Probable Starting Pitchers:
Probable Pitchers: Seth Lugo (Royals) — 1-1, 2.68 ERA
Slade Cecconi (Guardians) — 1-4, 6.56 ERA
The Royals will start Seth Lugo (1-1) against Slade Cecconi (1-4). Lugo and his team are 5-2-0 ATS this season when he starts. When Lugo starts as the favorite on the moneyline, his team records 2-1. When Cecconi starts, the Guardians are 2-5-0 against the spread. The Guardians are 1-5 in Cecconi’s six starts this season where they were the underdog on the moneyline.
Predictions and Odds:
All MLB win probability predictions and picks are from numberFire.
Prediction: Royals win (60.9%)
Kansas City is a -144 favorite on the moneyline, while Cleveland is a +122 on the road. The Guardians are +1.5 on the runline at +138 to cover, while the Royals are -166 to cover. An over/under of 9 has been set, with the over at -122 and the under at +100.
Season notes and team context:
The Royals have nine wins in 16 games this season when listed as the favorites. Kansas City is 3-2 in contests when bookmakers favor them by -144 or more on the moneyline. The Royals and their opponents have hit the over in 14 of their 35 games this season. Kansas City is 17-18-0 ATS in 35 games with a line this year.
The Guardians have gone 10-10 in games where they were the moneyline underdog (winning 50%). In moneyline underdog situations with odds of +122 or longer, Cleveland is 4-4 (50%). The Guardians have played in 37 games with a set over/under, going over the total 18 times (18-19-0). Cleveland is 19-18-0 ATS this season.
Bobby Witt Jr. leads Kansas City in slugging percentage (.422) thanks to 14 extra-base hits. He has a .279 batting average and an on-base percentage of .349. Among qualified hitters in baseball, his batting average ranks 40th, his on-base percentage ranks 65th, and he is 69th in slugging.
Maikel Garcia is batting .265 with nine doubles, a triple, three home runs and 15 walks.
